Gut Brain Axis IBS (Irritable Bowel Syndrome)

Diagnostics of irritable bowel-associated symptoms

Gut and brain are connected. They communicate bidirectionally via the so-called gut-brain axis. Professionally, irritable bowel syndrome is no longer considered just a gastrointestinal disorder. Rather, it is now recognized as a medically inexplicable disorder of the bidirectional communication between the gut and the brain.1

As part of our Gut-Brain-Axis IBS diagnostics, we determine histamine, GABA, tryptophan and serotonin in the stool. These form an important basis for the targeted treatment of the complex clinical picture of irritable bowel syndrome.

Gut-brain axis and associated symptoms

The disorders of the gut-brain interaction associated with irritable bowel syndrome manifest themselves in a variety of ways. Irritable bowel patients suffer from, among other things:

  • visceral hypersensitivity
  • pain
  • sleep disorders
  • motility disorders (diarrhea and/or constipation)
  • nausea and vomiting
  • inflammation

In the intestinal mucosa of those affected with irritable bowel syndrome, pathophysiological changes such as an excessively permeable intestinal epithelium (leaky gut syndrome) are also often found.2

Related diagnostic parameters



the intelligent microbiome diagnostics with resilience index, functional groups and FODMAP type

Abdominal discomfort

The biochemical parameters of KyberPlus clarify the causes for unclear abdominal discomfort.